Tg(TCRD)Talpha1,2mEtsKrg
Transgene Detail
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Symbol: |
Tg(TCRD)Talpha1,2mEtsKrg |
Name: |
transgene insertion Talpha1,2mEts, Michael S Krangel |
MGI ID: |
MGI:7398138 |
Synonyms: |
Talpha1,2mEts |
Transgene: |
Tg(TCRD)Talpha1,2mEtsKrg Location: unknown
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Alliance: |
Tg(TCRD)Talpha1,2mEtsKrg page
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Strain of Origin: |
(C57BL/6 x SJL/J)F2
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(TCRD)Talpha1,2mEtsKrg expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
human |
TRD (6964) |
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Mutation details: The transgene insert contains a 22.5-kb human TCRD gene minilocus consisting of germline Vdelta1, Vdelta2, Ddelta3, Jdelta1, Jdelta3, and Cdelta gene segments and all "intronic" sequence between, including enhancer sequence between Jdelta3 and Cdelta where Ets-binding site TCCTC was mutated to AGTTC.
(J:330514)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:330514 Roberts JL, et al., Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer. J Exp Med. 1997 Jan 6;185(1):131-40 |
All: |
1 reference(s) |
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