Tg(TCRD)Talpha1,2mTCFKrg
Transgene Detail
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| Symbol: |
Tg(TCRD)Talpha1,2mTCFKrg |
| Name: |
transgene insertion Talpha1,2mTCF, Michael S Krangel |
| MGI ID: |
MGI:7398137 |
| Synonyms: |
Talpha1,2mTCF |
| Transgene: |
Tg(TCRD)Talpha1,2mTCFKrg Location: unknown
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| Alliance: |
Tg(TCRD)Talpha1,2mTCFKrg page
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| Strain of Origin: |
(C57BL/6 x SJL/J)F2
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TCRD)Talpha1,2mTCFKrg expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| human |
TRD (6964) |
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Mutation details: The transgene insert contains a 22.5-kb human TCRD gene minilocus consisting of germline Vdelta1, Vdelta2, Ddelta3, Jdelta1, Jdelta3, and Cdelta gene segments and all "intronic" sequence between, including enhancer sequence between Jdelta3 and Cdelta where TCF/LEF-binding site CTTTGAA was mutated to CATAGAA.
(J:330514)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:330514 Roberts JL, et al., Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer. J Exp Med. 1997 Jan 6;185(1):131-40 |
| All: |
1 reference(s) |
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Analysis Tools
