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Gene Expression Data
Assay Details
Assay
Reference: J:225740 Snowball J, et al., Endodermal Wnt signaling is required for tracheal cartilage formation. Dev Biol. 2015 Sep 1;405(1):56-70
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7388676
Gene symbol: Axin2
Gene name: axin 2
Reporter: lacZ
Direct Detection
Results
Specimen 2A control: embryonic day 12.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Present 2A left
TS20: lung mesenchyme Present 2A left
TS20: trachea mesenchyme Present 2A left
Specimen 2A cKO: embryonic day 12.5; Axin2tm1Wbm/Axin2+, Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Ambiguous 2A right Nearly absent or not detected.
TS20: lung mesenchyme Ambiguous 2A right Nearly absent or not detected.
TS20: trachea mesenchyme Ambiguous 2A right Nearly absent or not detected.
Specimen 2B control-1: embryonic day 12.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Present Regionally restricted 2B left upper Expressed in the subepithelial mesenchymal cells of conducting airways.
TS20: lung mesenchyme Present Regionally restricted 2B left upper Expressed in lung periphery.
Specimen 2B control-2: embryonic day 12.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Present Regionally restricted 2B left lower Expressed in the subepithelial mesenchymal cells of conducting airways.
TS20: lung mesenchyme Present Regionally restricted 2B left lower Expressed in lung periphery.
Specimen 2B cKO-1: embryonic day 12.5; Axin2tm1Wbm/Axin2+, Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Ambiguous 2B right upper Nearly absent or not detected.
TS20: lung mesenchyme Ambiguous 2B right upper Nearly absent or not detected.
Specimen 2B cKO-2: embryonic day 12.5; Axin2tm1Wbm/Axin2+, Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Ambiguous 2B right lower Nearly absent or not detected.
TS20: lung mesenchyme Ambiguous 2B right lower Nearly absent or not detected.
Specimen 2C control: embryonic day 14.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS22: trachea mesenchyme Present Regionally restricted 2C right Expressed in the mesenchyme resembling the pattern of cartilaginous rings.
Specimen 2C cKO: embryonic day 14.5; Axin2tm1Wbm/Axin2+, Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: trachea mesenchyme Absent 2C left
Specimen 2E: embryonic day 14.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS22: trachea mesenchyme Present Regionally restricted 2E Expressed in the periphery of tracheal mesenchymal condensations.
Specimen 2F: embryonic day 14.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS22: trachea mesenchyme Present Regionally restricted 2F Expressed in the periphery of tracheal mesenchymal condensations.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory