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Gene Expression Data
Assay Details
Assay
Reference: J:186470 Lopes C, et al., Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
Assay type: RNA in situ
MGI Accession ID: MGI:7388631
Gene symbol: Trpm8
Gene name: transient receptor potential cation channel, subfamily M, member 8
Probe: TRPM8 probe1
Probe preparation: Antisense RNA
Results
Specimen 4D TRPM8 Control: postnatal day 30; Tlx3tm2.1Qima/? (more )
Note: Littermate control; genotype either fl/fl or fl/+.
Structure Level Pattern Image Note
TS28: lumbar dorsal root ganglion Present 4D TRPM8 Control
Specimen 4D TRPM8 Tlx3 CKO: postnatal day 30; Tlx3tm2.1Qima/Tlx3tm2.1Qima, Tg(Scn10a-cre)1Rkun/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lumbar dorsal root ganglion Weak 4D TRPM8 Tlx3 CKO Expression reduced by 45% compared to control.
Specimen 5A TRPM8 E16.5 Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lumbar dorsal root ganglion Present 5A TRPM8 E16.5 Control
Specimen 5A TRPM8 E16.5 Tlx3-/-: embryonic day 16.5; Tlx3tm1Sjk/Tlx3tm1Sjk (more )
Structure Level Pattern Image Note
TS24: lumbar dorsal root ganglion Present 5A TRPM8 E16.5 Tlx3-/- Expression still detected at E16.5.
Specimen 5A TRPM8 P0 Control: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lumbar dorsal root ganglion Present 5A TRPM8 P0 Control
Specimen 5A TRPM8 P0 Tlx3-/-: postnatal day 0; Tlx3tm1Sjk/Tlx3tm1Sjk (more )
Structure Cell Type Level Pattern Image Note
TS27: lumbar dorsal root ganglion neuron Trace Single cells 5A TRPM8 P0 Tlx3-/- Expression greatly reduced at P0. Weak expression in neurons
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory