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Gene Expression Data
Assay Details
Assay
Reference: J:328989 Patel SD, et al., Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388390
Gene symbol: Cdkn1c
Gene name: cyclin dependent kinase inhibitor 1C
Antibody: Anti-p57kip2 (H-91; sc-8298)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 9 Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens Present Regionally restricted 9A control row 1 , 9A control row 2 Expression is in the transition zone.
TS24: lens fiber Present 9A control row 2 , 9A control row 1
Specimen 9 KO1: embryonic day 16.5; Mafgtm1Jeng/Mafgtm1Jeng, Mafktm1Jeng/Mafktm1Jeng (more )
Structure Level Pattern Image Note
TS24: lens Strong Regionally restricted 9A Mafg-/-:Mafk-/- row 2 , 9A Mafg-/-:Mafk-/- row 1 In this mutant protein levels are elevated in the transition zone compared to controls.
TS24: lens fiber Strong 9A Mafg-/-:Mafk-/- row 1 , 9A Mafg-/-:Mafk-/- row 2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory