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Gene Expression Data
Assay Details
Assay
Reference: J:217173 Lockhart MM, et al., Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction. Dev Biol. 2014 Dec 1;396(1):8-18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388205
Gene symbol: Vcan
Gene name: versican
Antibody: anti-Versican beta
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 10A/B: postnatal week 4; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mitral valve Present Regionally restricted 10A , 10B Expressed in the distal tip of the properly formed leaflet.
TS28: aortic valve Present Regionally restricted 10A Expressed in the distal tip of the properly formed leaflet.
Specimen 10D/E: postnatal week 4; Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mitral valve Present 10E , 10D Enlarged distal portion of the left parietal leaflet contained abnormally large amounts of expression.
TS28: aortic valve Present Regionally restricted 10D Expressed in the distal tip of the properly formed leaflet.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory