Gene Expression Data
Assay Details
Assay
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Reference:
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J:269548
Ramirez DM, et al., Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain. J Comp Neurol. 2008 Apr 10;507(5):1676-93
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7388174
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Gene symbol:
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Cyp46a1
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Gene name:
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cytochrome P450, family 46, subfamily a, polypeptide 1
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Antibody:
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1A7
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
7A:
postnatal month 3
(more )
Specimen
7A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 3
|
Sex:
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Female
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: hippocampus CA1 |
pyramidal neuron |
Strong |
Regionally restricted |
7A
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Expression is in the cell bodies and dendrites of pyramidal neurons.
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Specimen
7B:
(close )
Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Cyp46a1tm1Rus/Cyp46a1tm1Rus
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Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7C:
postnatal month 3
(more )
Specimen
7C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7D:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7E:
postnatal month 14
(more )
Specimen
7E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 14
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: hippocampus CA1 |
pyramidal neuron |
Present |
Regionally restricted |
7E
|
Expression is in the cell bodies and dendrites of pyramidal neurons.
|
Specimen
7F:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 14
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
8A:
postnatal month 3
(more )
Specimen
8A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
8B:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
8C:
postnatal month 3
(more )
Specimen
8C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
8D:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
9A:
postnatal month 3
(more )
Specimen
9A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
9B:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 3
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
10A:
postnatal month 3
(more )
Specimen
10A:
(close )
Genetic Background:
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involves: 129S6/SvEv * C57BL/6J * SJL/J
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Age:
|
postnatal month 3
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Sex:
|
Male
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Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
10B:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 3
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
(close )
Genetic Background:
|
involves: 129 * C57BL/6J
|
Mutant Allele(s):
|
Cyp46a1tm1Rus/Cyp46a1tm1Rus
|
Age:
|
postnatal month 3
|
Sex:
|
Male
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
|