About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:311142 Sun H, et al., Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing. Front Cell Dev Biol. 2021;9:690955
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384740
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 6D: postnatal day 0 (more )
Note: Double labeled: red - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlea auditory hair cell Present 6D

Specimen 6E: postnatal day 0; Adgra3tm1Dgen/Adgra3+ (more )
Note: Double labeled: red - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlea auditory hair cell Present 6E No differences in cochlear length compared with the wild-type.

Specimen 6F: postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Double labeled: red - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlea auditory hair cell Present 6F No differences in cochlear length compared with the wild-type.

Specimen 6G: embryonic day 15.5 (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present 6G

Specimen 6H: embryonic day 15.5; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present 6H Similar as in the wild-type.

Specimen 6I: embryonic day 18.5 (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 6I
TS26: cochlear duct epithelium cochlear outer hair cell Present 6I

Specimen 6J: embryonic day 18.5; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 6J Similar as in the wild-type.
TS26: cochlear duct epithelium cochlear outer hair cell Present 6J Similar as in the wild-type.

Specimen 6K: postnatal day 0 (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 6K
TS27: cochlear duct epithelium cochlear outer hair cell Present 6K

Specimen 6L: postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 6L Similar as in the wild-type.
TS27: cochlear duct epithelium cochlear outer hair cell Present 6L Similar as in the wild-type.

Specimen 6M: postnatal day 4 (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6M
TS28: cochlear duct epithelium cochlear outer hair cell Present 6M

Specimen 6N: postnatal day 4; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6N Similar as in the wild-type.
TS28: cochlear duct epithelium cochlear outer hair cell Present 6N Similar as in the wild-type.

Specimen 6O: postnatal day 30 (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6O
TS28: cochlear duct epithelium cochlear outer hair cell Present 6O

Specimen 6P: postnatal day 30; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: red - Myo7a; blue - Sox2 (assay MGI:7384748); green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6P Similar as in the wild-type.
TS28: cochlear duct epithelium cochlear outer hair cell Present 6P Similar as in the wild-type.

Specimen S2B: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present S2B

Specimen S2C: embryonic day 15.5; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present S2C Similar as in the wild-type.

Specimen S2D: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present S2D
TS26: cochlear duct epithelium cochlear outer hair cell Present S2D

Specimen S2E: embryonic day 18.5; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present S2E Similar as in the wild-type.
TS26: cochlear duct epithelium cochlear outer hair cell Present S2E Similar as in the wild-type.

Specimen S2F: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present S2F
TS27: cochlear duct epithelium cochlear outer hair cell Present S2F

Specimen S2G: postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present S2G Similar as in the wild-type.
TS27: cochlear duct epithelium cochlear outer hair cell Present S2G Similar as in the wild-type.

Specimen S2H: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present S2H
TS28: cochlear duct epithelium cochlear outer hair cell Present S2H

Specimen S2I: postnatal day 4; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present S2I Similar as in the wild-type.
TS28: cochlear duct epithelium cochlear outer hair cell Present S2I Similar as in the wild-type.

Specimen S2J: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present S2J
TS28: cochlear duct epithelium cochlear outer hair cell Present S2J

Specimen S2K: postnatal day 30; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present S2K Similar as in the wild-type.
TS28: cochlear duct epithelium cochlear outer hair cell Present S2K Similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory