About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:116891 Tanaka M, et al., Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem. 2006 Sep 1;281(35):25822-30
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7384468
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Reporter: lacZ
Direct Detection
Results
Specimen 5B E8.5+/+ embryo: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: vascular system endothelial cell of vascular tree Present 5B E8.5 +/+ 1
Specimen 5B E8.5-/- embryo: embryonic day 8.5; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: vascular system endothelial cell of vascular tree Present 5B E8.5 -/- 1 Vasculature defects in the head were noted.
Specimen 5B E8.5+/+ heart region: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: sinus venosus endothelial cell of vascular tree Present 5B E8.5 +/+ 2
Specimen 5B E8.5-/- heart region: embryonic day 8.5; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: vascular system endothelial cell of vascular tree Present Regionally restricted 5B E8.5 -/- 2 Sinus venosus defects were noted.
Specimen 5B E8.5+/+ dorsal aorta: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: dorsal aorta blood vessel endothelial cell Present 5B E8.5 +/+ 3
Specimen 5B E8.5-/- dorsal aorta: embryonic day 8.5; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: dorsal aorta blood vessel endothelial cell Present 5B E8.5 -/- 3
Specimen 5B E8.5+/+ yolk sac: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: yolk sac blood vessel blood vessel endothelial cell Present 5B E8.5 +/+ 4
Specimen 5B E8.5-/- yolk sac: embryonic day 8.5; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS13: yolk sac blood vessel blood vessel endothelial cell Present 5B E8.5 -/- 4
Specimen 5B E9.0+/+ yolk sac: embryonic day 9.0; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS14: yolk sac blood vessel blood vessel endothelial cell Present 5B E9.0 +/+
Specimen 5B E9.0-/- yolk sac: embryonic day 9.0; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS14: yolk sac blood vessel blood vessel endothelial cell Present 5B E9.0 -/- Both normal and abnormal yolk sac vessels were noted in the mutant.
Specimen 5B E9.5+/+ yolk sac: embryonic day 9.5; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood vessel blood vessel endothelial cell Present 5B E9.5 +/+ upper
Specimen 5B E9.5-/- yolk sac: embryonic day 9.5; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood vessel blood vessel endothelial cell Present 5B E9.5 -/- upper Severe vascular defects were noted. No fine blood vessels had developed in the mutant.
Specimen 5B E9.5+/+ yolk sac (lower): embryonic day 9.5; Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood vessel blood vessel endothelial cell Present 5B E9.5 +/+ lower
Specimen 5B E9.5-/- yolk sac (lower): embryonic day 9.5; Enpp2tm1Lex/Enpp2tm1Lex, Kdrtm1Jrt/Kdr+ (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood vessel blood vessel endothelial cell Present 5B E9.5 -/- lower Severe vascular defects were noted. No fine blood vessels had developed in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory