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Lmx1bem1(cre)Jgeer
Endonuclease-mediated Allele Detail
Summary
Symbol: Lmx1bem1(cre)Jgeer
Name: LIM homeobox transcription factor 1 beta; endonuclease-mediated mutation 1, Joel C Geerling
MGI ID: MGI:7384278
Synonyms: Lmx1b-2A-Cre
Gene: Lmx1b  Location: Chr2:33450977-33530620 bp, - strand  Genetic Position: Chr2, 22.48 cM
Alliance: Lmx1bem1(cre)Jgeer page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Lmx1bem1(cre)Jgeer expression driven by 1 gene
 
Mutation details: The guide (AGCTCTGCATGGAGTAGAGC) was designed to cut near the stop codon of the LIM homeobox transcription factor 1 beta (Lmxb1) gene and to insert a viral 2A oligopeptide (2A) self-cleaving peptide fused to a Cre recombinase sequence. (J:101977, J:370260)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lmx1b (mouse)
Summary of all recombinase alleles driven by Lmx1b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lmx1b Mutation:  17 strains or lines available
References
Original:  J:370260 Grady FS, et al., Parabrachial Foxp2-expressing neurons are necessary for sustaining core body temperature in the cold. iScience. 2025 Aug 15;28(8):112764
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/05/2025
MGI 6.24 		The Jackson Laboratory