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Gene Expression Data
Assay Details
Assay
Reference: J:231358 Cameron TL, et al., Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization. Osteoarthritis Cartilage. 2015 Apr;23(4):661-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7383022
Gene symbol: Ihh
Gene name: Indian hedgehog
Results
Specimen 4G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epiphyseal plate proliferative zone Present Regionally restricted 4G Expression in proliferating chondrocytes.
TS23: tibia Present Regionally restricted 4G Expression in developing bone collar.
Specimen 4H: embryonic day 15.5; Xbp1tm2Glm/Xbp1tm2Glm, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: epiphyseal plate proliferative zone Present Regionally restricted 4H Expression levels in proliferating chondrocytes comparable to wild type.
TS23: tibia Present Regionally restricted 4H No expression in developing bone collar.
Specimen 4I: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate proliferative zone Present Regionally restricted 4I Expression in proliferating chondrocytes.
TS28: tibia epiphysis Present Regionally restricted 4I Expression in proliferating chondrocytes.
Specimen 4J: postnatal week 2; Xbp1tm2Glm/Xbp1tm2Glm, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: epiphyseal plate proliferative zone Present Regionally restricted 4J Expression levels in proliferating chondrocytes comparable to wild type.
TS28: tibia epiphysis Present Regionally restricted 4J Expression levels in proliferating chondrocytes comparable to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory