Gene Expression Data
Assay Details
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Assay
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Reference:
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J:260124
Goldmann T, et al., Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat Immunol. 2016 Jul;17(7):797-805
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7382873
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Gene symbol:
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Aif1
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Gene name:
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allograft inflammatory factor 1
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Results
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Specimen
1a left:
postnatal
(more  )
Specimen
1a left:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain |
microglial cell |
Present |
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1a left
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| TS28: brain |
perivascular macrophage |
Present |
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1a left
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| TS28: brain meninges |
meningeal macrophage |
Present |
Regionally restricted |
1a left
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Expression was detected in subdural meninges.
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Specimen
1a right:
postnatal
(more )
Specimen
1a right:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6c Meninges WT:
postnatal adult
(more )
Specimen
6c Meninges WT:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain meninges |
meningeal macrophage |
Present |
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6c Meninges WT
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Specimen
6c Meninges Ccr2-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * FVB/N
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Mutant Allele(s):
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Ccr2tm2.1Ifc/Ccr2tm2.1Ifc
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: meninges |
meningeal macrophage |
Present |
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6c Meninges Ccr2-/-
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Normal proportions of meningeal macrophages were seen in the Ccr2-/- mice.
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Specimen
6c Perivascular space WT:
postnatal adult
(more )
Specimen
6c Perivascular space WT:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain |
perivascular macrophage |
Present |
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6c Perivascular space WT
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Specimen
6c Perivascular space Ccr2-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * FVB/N
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Mutant Allele(s):
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Ccr2tm2.1Ifc/Ccr2tm2.1Ifc
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain |
perivascular macrophage |
Present |
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6c Perivascular space Ccr2-/-
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Normal proportions of perivascular space macrophages were seen in the Ccr2-/- mice.
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Specimen
6c Choroid plexus WT:
postnatal adult
(more )
Specimen
6c Choroid plexus WT:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6c Choroid plexus Ccr2-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * FVB/N
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Mutant Allele(s):
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Ccr2tm2.1Ifc/Ccr2tm2.1Ifc
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: choroid plexus epithelium |
choroid plexus macrophage |
Present |
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6c Choroid plexus Ccr2-/-
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Choroid plexus macrophages were reduced in the Ccr2-deficient mice.
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| TS28: choroid plexus stroma |
choroid plexus macrophage |
Present |
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6c Choroid plexus Ccr2-/-
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Choroid plexus macrophages were reduced in the Ccr2-deficient mice.
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Specimen
S4a WT Meninges:
postnatal adult
(more )
Specimen
S4a WT Meninges:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain meninges |
meningeal macrophage |
Present |
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S4a Meninges top
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Specimen
S4a WT Perivascular space:
postnatal adult
(more )
Specimen
S4a WT Perivascular space:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain |
perivascular macrophage |
Present |
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S4a Perivascular space top
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Specimen
S4a WT Choroid plexus:
postnatal adult
(more )
Specimen
S4a WT Choroid plexus:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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