Tg(Nppa-lacZ)m-0.7-p4Vmc
Transgene Detail
|
|
| Symbol: |
Tg(Nppa-lacZ)m-0.7-p4Vmc |
| Name: |
transgene insertion m-0.7-p4, Vincent M Christoffels |
| MGI ID: |
MGI:7382813 |
| Synonyms: |
-0.7/+4mLacZ |
| Transgene: |
Tg(Nppa-lacZ)m-0.7-p4Vmc Location: unknown
|
| Alliance: |
Tg(Nppa-lacZ)m-0.7-p4Vmc page
|
|
| Strain of Origin: |
Not Applicable
|
|
| Transgene Type: |
|
Transgenic (Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The 638/+70 bp mouse Nppa regulatory region sequence, containing the promoter and silencer and enhancer sequences, is located upstream of a beta-globin/IgG chimeric intron, nls sequence, the lacZ beta-galactosidase gene, bovine GH poly(A) signal sequence and the remainder of the Nppa genomic sequence to +4 kb downstream relative to the transcription start site. The regulatory sequence drives expression in the embryonic atrial and ventricular chamber myocardium.
(J:278530)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:278530 Horsthuis T, et al., Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ Res. 2008 Apr 11;102(7):849-59 |
| All: |
1 reference(s) |
|
Analysis Tools
