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Gene Expression Data
Assay Details
Assay
Reference: J:316578 Lade A, et al., Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7380694
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin (#610153), clone 14
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Antibody detects both the full-length and truncated forms.
Results
Specimen 2D E12.5: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: liver hepatocyte Present 2D E12.5 middle Truncated forms (regions positive with anti-Cterminal but not anti-N-terminal antibody) expression. Present at membrane and in the cytoplasm and nuclei.
TS20: bile duct epithelium Present 2D E12.5 middle Present at membrane and in the cytoplasm and nuclei.

Specimen 2D E18.5: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: liver hepatocyte Strong 2D E18.5 middle Truncated forms (regions positive with anti-Cterminal but not anti-N-terminal antibody) expression. Membranous and nuclear staining were seen.
TS26: bile duct epithelium Present 2D E18.5 middle Limited to the nucleus and cytoplasm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory