Results
|
Specimen
5a/b:
postnatal adult
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
5a/b:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Specimen
5d/f:
postnatal adult
(more )
Note: Double labeled: green - Septin7; red - Tubb3 (assay MGI:7380402).
Specimen
5d/f:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - Tubb3 (assay MGI:7380402).
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Present |
Regionally restricted |
5f
,
5d
|
Co-expression with Tubb3 in punctate structures but not in filament-like structure.
|
Specimen
5g/i:
postnatal adult
(more )
Note: Double labeled: green - Septin7; red - Syp (assay MGI:7380405).
Specimen
5g/i:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - Syp (assay MGI:7380405).
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Present |
Regionally restricted |
5g inset
,
5i inset`
,
5g
,
5i
|
Co-expression with synaptophysin in punctate structure below inner hair cells and around basal portion of outer hair cells.
|
Specimen
5j/l:
postnatal adult
(more )
Note: Double labeled: green - Septin7; red - acetylated tubulin.
Specimen
5j/l:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - acetylated tubulin.
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Deiter's cell |
Present |
Regionally restricted |
5l
,
5j
|
Expression in filament-like structure co-expressed with acetylated alpha tubulin.
|
Specimen
6c/f:
postnatal adult
(more )
Note: Double labeled: green - Septin7; red - Myo7a (assay MGI:7380409).
Specimen
6c/f:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - Myo7a (assay MGI:7380409).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Deiter's cell |
Present |
Regionally restricted |
6c
,
6f
|
Expression in filament-like structures originating from basilar membrane and extending to apices of outer hair cells, running outside of outer hair cells. Expression in phalangeal process of Deiters' cells.
|
Specimen
8d/f:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Septin5tm1Wtr/Septin5tm1Wtr
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - Syp (assay MGI:7380405).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Deiter's cell |
Present |
|
8f
,
8d
|
Expression pattern similar to that of wild type cochlea in pillar cells, Deiters' cells and presynaptic vesicles.
|
TS28: organ of Corti |
pillar cell |
Present |
|
8f
,
8d
|
Expression pattern similar to that of wild type cochlea in pillar cells, Deiters' cells and presynaptic vesicles.
|
Specimen
10a/c:
embryonic day 13.0
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
10a/c:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 13.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Specimen
10d/f:
embryonic day 15.0
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
10d/f:
(close )
Genetic Background:
|
ICR
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: cochlear duct epithelium |
Strong |
Widespread |
10d
,
10f
|
Similar expression maintained until E15 with more intense expression level.
|
Specimen
10g/i:
postnatal day 1
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
10g/i:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 1
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Specimen
10j/l:
postnatal day 2
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
10j/l:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 2
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: organ of Corti |
pillar cell |
Strong |
Regionally restricted |
10j
,
10l
|
Stronger expression at apical portion of pillar cells through P2 and P3.
|
Specimen
10m/o:
postnatal day 3
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
10m/o:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 3
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: organ of Corti |
Deiter's cell |
Strong |
|
10m
,
10o
|
Stronger expression than in other epithelial cells in pillar cells, Deiters' cells, Hensen't cells and Claudius cells.
|
TS27: organ of Corti |
Hensen cell |
Strong |
|
10m
,
10o
|
Stronger expression than in other epithelial cells in pillar cells, Deiters' cells, Hensen't cells and Claudius cells.
|
TS27: organ of Corti |
pillar cell |
Strong |
|
10m
,
10o
|
Stronger expression than in other epithelial cells in pillar cells, Deiters' cells, Hensen't cells and Claudius cells.
|
TS27: cochlea |
Claudius cell |
Strong |
|
10m
,
10o
|
|
Specimen
10p/r:
postnatal day 7
(more )
Note: Double labeled: green - Septin7; red - F-actin.
Specimen
10p/r:
(close )
Genetic Background:
|
ICR
|
Age:
|
postnatal day 7
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Septin7; red - F-actin.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cochlea |
Present |
Regionally restricted |
10r
,
10p
|
Expression pattern similar to that in adult cochlea. No expression in presynaptic vesicles.
|
|