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Tg(Tnni3-lacZ)#Vmc
Transgene Detail
Summary
Symbol: Tg(Tnni3-lacZ)#Vmc
Name: transgene insertion, Vincent M Christoffels
MGI ID: MGI:7378841
Synonyms: cTnI-nlacZ
Transgene: Tg(Tnni3-lacZ)#Vmc  Location: unknown  
Alliance: Tg(Tnni3-lacZ)#Vmc page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe 230/+126 bp Tnni3 promoter sequence, flanked by chicken beta-globin locus insulator sequence, is placed upstream of a beta-globin/IgG chimeric intron, nls sequence, the lacZ beta-galactosidase gene and bovine GH poly(A) signal sequence. The promoter drives expression in the embryonic myocardium of the atrioventricular canal. (J:76656)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:76656 Habets PE, et al., Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev. 2002 May 15;16(10):1234-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory