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Gene Expression Data
Assay Details
Assay
Reference: J:309724 Rux D, et al., Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice. Dev Biol. 2021 Sep;477:49-63
Assay type: RNA in situ
MGI Accession ID: MGI:7378537
Gene symbol: Hoxc11
Gene name: homeobox C11
Probe: Mm-Hoxc11 (1049161)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope was performed using the RED2.5 detection system.
Results
Specimen 7C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb Absent 7C
Specimen 8B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hindlimb Present Regionally restricted 8B Expression was largely restricted to the posterior region of zeugopod and display much lower expression in zeugopod joints.
TS23: zeugopod Present Regionally restricted 8B Expression was largely restricted to the posterior region of zeugopod and display much lower expression in zeugopod joints.
TS23: ankle Present Regionally restricted 8B Expression was detected in the developing achilles tendon.
Specimen 8E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: ankle Weak 8E
TS27: tendo calcaneus Weak 8E
Specimen 8G: postnatal newborn (more )
Note: medial region.
Structure Level Pattern Image Note
TS27: knee joint Absent 8G Hoxc11
Specimen 8H: postnatal newborn (more )
Note: center region.
Structure Level Pattern Image Note
TS27: knee joint Absent 8H Hoxc11
Specimen 8I: postnatal newborn (more )
Note: lateral region.
Structure Level Pattern Image Note
TS27: knee joint Absent 8I Hoxc11
Specimen 8J: postnatal newborn (more )
Note: patella region.
Structure Level Pattern Image Note
TS27: knee joint Absent 8J Hoxc11
Specimen 8K: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: articular cartilage Ambiguous 8K Hoxc11
Specimen 8L: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: synovium Ambiguous 8L Hoxc11
Specimen 8M: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: knee joint Ambiguous 8M Hoxc11
Specimen 8N: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: ligament Present Regionally restricted 8N Hoxc11 Expression was detected in the knee ligament.
Specimen 8O: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: bone marrow Present Regionally restricted 8O Hoxc11 Expression was detected in the tibia bone marrow.
Specimen S5B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: shoulder Absent S5B
Specimen S5E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hip Absent S5E
Specimen S5H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: sacral vertebral cartilage condensation Present S5H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory