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Gene Expression Data
Assay Details
Assay
Reference: J:71941 Baumgart E, et al., Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Am J Pathol. 2001 Oct;159(4):1477-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378395
Gene symbol: Uqcrc2
Gene name: ubiquinol cytochrome c reductase core protein 2
Antibody: anti-Complex III, subunit core I (13G12AF12BB11)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4G: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: liver hepatocyte Present Regionally restricted 4G Expression in mitochondria.

Specimen 4H: embryonic day 18.5; Pex5tm1Baes/Pex5tm1Baes (more )
Structure Cell Type Level Pattern Image Note
TS26: liver hepatocyte Weak Non-Uniform 4H Reduction of overall expression intensity, lower than that seen for complex I. Marked intercellular heterogeneity in distribution of expression compared to wildtype.

Specimen 4J: embryonic day 18.5; Pex5tm1Baes/Pex5tm1Baes (more )
Structure Cell Type Level Pattern Image Note
TS26: liver hepatocyte Weak Non-Uniform 4J Reduction of overall expression intensity, lower than that seen for complex I. Marked intercellular heterogeneity in distribution of expression compared to wildtype.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory