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Gene Expression Data
Assay Details
Assay
Reference: J:283039 Giralt A, et al., Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020 Jan;323:113095
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7367515
Gene symbol: Ikzf2
Gene name: IKAROS family zinc finger 2
Results
Specimen 1A CA1 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 1A E16.5 Expression in hippocampal plate of CA1.
Specimen 1A CA1 E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hippocampus CA1 Present Regionally restricted 1A E18.5 Expression in hippocampal plate of CA1.
Specimen 1A CA1 P2: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Present Regionally restricted 1A P2 Expression in hippocampal plate of CA1.
Specimen 1A CA1 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 1A P7 Expression in hippocampal plate of CA1.
Specimen 1B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 1B Expression in hippocampal plate of CA1. No expression in CA3.
TS24: dentate gyrus Absent 1B
Specimen 1C: embryonic day 16.5 (more )
Note: Double labeled: red - Helios (Ikzf2); green - Mki67 (assay MGI:7367518).
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 1C Expression in hippocampal plate of CA1.
Specimen 1D: embryonic day 16.5 (more )
Note: Double labeled: red - Helios (Ikzf2); green - Nes (assay MGI:7367519).
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 1D Expression in hippocampal plate of CA1.
Specimen 1G: postnatal day 0 (more )
Note: Double labeled: green - Helios (Ikzf2); red - Map2 (assay MGI:7367520).
Structure Cell Type Level Pattern Image Note
TS27: CA1 pyramidal cell layer hippocampal pyramidal neuron Present 1G inset , 1G Co-localization with Map2 expression. All expressing cells displayed typical shape of pyramidal neurons.
Specimen 1H: postnatal day 0 (more )
Note: Double labeled: green - Helios (Ikzf2); red - Calb1 (assay MGI:7367521).
Structure Cell Type Level Pattern Image Note
TS27: CA1 pyramidal cell layer hippocampal pyramidal neuron Present 1H , 1H inset Co-expression with Calb1 in pyramidal neurons.
TS27: hippocampus stratum radiatum hippocampal interneuron Absent 1H inset , 1H No expression in Calb1-expressing interneurons.
Specimen 6C He+/+: postnatal day 0 (more )
Note: Double labeled: red - Helios (Ikzf2); green - Vsnl1 (assay MGI:7367522).
Structure Level Pattern Image Note
TS27: hippocampus CA1 Present Regionally restricted 6C He+/+ Expression in hippocampal plate of CA1.
Specimen 6C He-/-: postnatal day 0; Ikzf2tm1Kast/Ikzf2tm1Kast (more )
Note: Double labeled: red - Helios (Ikzf2); green - Vsnl1 (assay MGI:7367522).
Structure Level Pattern Image Note
TS27: hippocampus CA1 Absent 6C He-/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory