Gene Expression Data
Assay Details
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Assay
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Reference:
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J:110617
Stottmann RW, et al., The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol. 2006 Jul 15;295(2):647-63
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7367222
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Gene symbol:
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Pax1
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Gene name:
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paired box 1
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Probe:
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Pax1 probe3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5A:
embryonic day 10.0
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: sclerotome |
Present |
Non-Uniform |
5E
,
5F
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Expression decreased in the region between the limbs in the mutant compared with wild type. However, expression level was comparable to wild type control embryos caudal to the hindlimb bud.
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Specimen
not shown control:
embryonic day 11.0
(more )
Specimen
not shown control:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
not shown Nog-/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: sclerotome |
Present |
Non-Uniform |
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Expression decreased in the region between the limbs in the mutant compared with wild type. However, expression level was comparable to wild type control embryos caudal to the hindlimb bud.
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Specimen
8K:
embryonic day 10.0; Nogtm1Amc/Nog +
(more )
Specimen
8K:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nog+
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
8L:
embryonic day 10.0; Nogtm1Amc/Nog +
(more )
Specimen
8L:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nog+
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
8M:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129S6/SvEvTac
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Mutant Allele(s):
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Bmp4tm2Blh/Bmp4+
Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: sclerotome |
Present |
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8M
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Nog-/-;Bmp4+/- mutant expression was similar to the control embryos, rather than reduced as in Nog-/- mutants.
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Specimen
8N:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129S6/SvEvTac
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Mutant Allele(s):
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Bmp4tm2Blh/Bmp4+
Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: sclerotome |
Present |
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8N
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Nog-/-;Bmp4+/- mutant expression was similar to the control embryos, rather than reduced as in Nog-/- mutants.
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Analysis Tools
