Gene Expression Data
Assay Details
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Assay
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Reference:
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J:110617
Stottmann RW, et al., The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol. 2006 Jul 15;295(2):647-63
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7367205
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Gene symbol:
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Msx2
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Gene name:
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msh homeobox 2
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Probe:
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Msx2 probe5
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
3J:
embryonic day 8.0
(more  )
Specimen
3J:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3K:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: future hindbrain |
Present |
Regionally restricted |
3K
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Msx2 was upregulated dorsally in both exencephalic and non-exencephalic mutant embryos.
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| TS12: future midbrain |
Present |
Regionally restricted |
3K
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Msx2 was upregulated dorsally in both exencephalic and non-exencephalic mutant embryos.
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Specimen
3L:
embryonic day 9.0
(more )
Specimen
3L:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3M:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: future hindbrain |
Present |
Regionally restricted |
3M
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Msx2 was upregulated dorsally in both exencephalic and non-exencephalic mutant embryos.
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| TS14: future midbrain |
Present |
Regionally restricted |
3M
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Msx2 was upregulated dorsally in both exencephalic and non-exencephalic mutant embryos.
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Specimen
5K:
embryonic day 9.0
(more )
Specimen
5K:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5O:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: trunk |
Present |
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5P
,
5O
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The overall intensity of expression between the limb buds was not profoundly affected, but the spatial domain of expression was increased in the mutant embryos.
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Analysis Tools