About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:116586 Li H, et al., Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning. Mol Cell Neurosci. 2006 Oct;33(2):136-49
Assay type: RNA in situ
MGI Accession ID: MGI:7367165
Gene symbol: Tenm4
Gene name: teneurin transmembrane protein 4
Probe: Odz4 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present Graded 3D Expression is in a rostral low to caudal high gradient.
TS23: cerebral cortex ventricular layer Present Graded 3D Expression is in a rostral low to caudal high gradient.
TS23: cortical plate Present Graded 3D Expression is in a rostral low to caudal high gradient.
TS23: hippocampus Present 3D
TS23: thalamus Present 3D

Specimen 3D': embryonic day 15.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Weak 3D' In this mutant the expression gradient has almost completely flattened out compared to wild-type.
TS23: cerebral cortex ventricular layer Weak 3D' In this mutant the expression gradient has almost completely flattened out compared to wild-type.
TS23: cortical plate Weak 3D' In this mutant the expression gradient has almost completely flattened out compared to wild-type.
TS23: hippocampus Present 3D' Expression in this tissue was less affected in this mutant compared to wild-type.
TS23: thalamus Present 3D' Expression in this tissue was less affected in this mutant compared to wild-type.

Specimen 4E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Graded 4E Expression is in a rostral low to caudal high gradient.
TS26: corpus striatum Present 4E
TS26: dentate gyrus Present 4E
TS26: hippocampus Present 4E
TS26: main olfactory bulb Present 4E
TS26: thalamus Present 4E
TS26: cortical plate Present Graded 4E Expression increased from anterior to posterior.
TS26: cerebral cortex subventricular zone Present Uniform 4E
TS26: cerebral cortex ventricular zone Present Uniform 4E
TS26: neocortex Present Regionally restricted 4E Expression is uniform in layer V.

Specimen 4E': embryonic day 18.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS26: cortical plate Weak Regionally restricted 4E' In this mutant the expressing region was reduced and had shifted towards the most posterior end compared to wild-type.
TS26: cerebral cortex subventricular zone Present 4E' The band of expressing cells was broader compared to wild-type.
TS26: cerebral cortex ventricular zone Present 4E' The band of expressing cells was broader compared to wild-type.
TS26: neocortex Present Regionally restricted 4E' Expression in layer V was similar to wild-type.

Specimen 4F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present 4F
TS26: dentate gyrus Present 4F
TS26: hippocampus Present 4F
TS26: main olfactory bulb Present 4F
TS26: thalamus Present 4F
TS26: cerebral cortex Present Graded 4F Expression is in a rostral low to caudal high gradient.
TS26: cortical plate Present Graded 4F Expression increased from anterior to posterior.
TS26: cerebral cortex subventricular zone Present Uniform 4F
TS26: cerebral cortex ventricular zone Present Uniform 4F
TS26: neocortex Present Regionally restricted 4F Expression is uniform in layer V.

Specimen 4F': embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Strong 4F'
TS26: cortical plate Strong Regionally restricted 4F' In this mutant the expressing area has expanded/shifted towards the anterior.
TS26: cerebral cortex subventricular zone Present 4F' The band of expressing cells was broader compared to wild-type.
TS26: cerebral cortex ventricular zone Present 4F' The band of expressing cells was broader compared to wild-type.

Specimen 5D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present Graded 5D Expression is differentiating cells in a rostral low to caudal high gradient.
TS23: cerebral cortex subventricular zone Present Graded 5D Expression is proliferating cells in a rostral low to caudal high gradient.
TS23: cerebral cortex ventricular layer Present Graded 5D Expression is proliferating cells in a rostral low to caudal high gradient.
TS23: corpus striatum Present 5D
TS23: hippocampus Present 5D
TS23: main olfactory bulb Present 5D
TS23: thalamus Present 5D

Specimen 5H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Graded 5H Expression is in a rostral low to caudal high gradient.
TS26: cerebral cortex ventricular zone Present Graded 5H Expression is in a rostral low to caudal high gradient.
TS26: cortical plate Present Graded 5H Expression is in a rostral low to caudal high gradient.
TS26: neocortex region Present Regionally restricted 5H Expression is in the orbital area.
TS26: insular cortex Present 5H

Specimen 6D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Present Graded 6D Expression is in a rostral low to caudal high gradient.
TS27: cerebral cortex ventricular zone Present Graded 6D Expression is in a rostral low to caudal high gradient.
TS27: cortical plate Present Graded 6D Expression is in a rostral low to caudal high gradient.
TS27: cortical layer V Present Graded 6D Expression is in a decreasing gradient from the posterior part to the most anterior part of cortex.
TS27: visual cortex Strong 6D
TS27: corpus striatum Present 6D
TS27: insular cortex Present 6D
TS27: thalamus Present 6D
TS27: neocortex region Present Regionally restricted 6D Expression is in the orbital area.
TS27: hippocampus Present Regionally restricted 6D

Specimen 7D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer V Very strong Graded 7D Expression is rostral low and caudal high.
TS28: cortical layer II Strong Graded 7D Expression is rostral low and caudal high. Expression terminates abruptly at the border between somatosensory and visual area.
TS28: cortical layer III Strong Graded 7D Expression is rostral low and caudal high. Expression terminates abruptly at the border between somatosensory and visual area.
TS28: cortical layer IV Strong Graded 7D Expression is rostral low and caudal high. Expression terminates abruptly at the border between somatosensory and visual area.
TS28: cortical layer VI Strong Graded 7D Expression is rostral low and caudal high. Expression terminates abruptly at the border between somatosensory and visual area.
TS28: cortical layer I Present Graded 7D Expression is rostral low and caudal high.
TS28: hippocampus CA1 Strong 7D
TS28: dentate gyrus Present 7D

Specimen 8D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Graded 8D Expression is in a high dorsal/medial to low ventral/lateral gradient.
TS23: dorsal thalamus Present Regionally restricted 8D Expression is in in the posterior complex and centrolateral nucleus and is absent in the ventroposterior nucleus.
TS23: dorsal lateral geniculate nucleus Present 8D
TS23: geniculate thalamic group Present Regionally restricted 8D Expression is in the ventral subdivision of medial geniculate nucleus.

Specimen 8H: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present Graded 8H Expression is in in a high medial and low lateral gradient.
TS27: dorsal lateral geniculate nucleus Strong 8H
TS27: lateral posterior thalamic nucleus Strong 8H
TS27: visual cortex Strong 8H
TS27: central lateral thalamic nucleus Present 8H
TS27: posterior thalamic group Present 8H

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Weak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory