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Gene Expression Data
Assay Details
Assay
Reference: J:190629 Niimori D, et al., Tsukushi controls the hair cycle by regulating TGF-beta1 signaling. Dev Biol. 2012 Dec 1;372(1):81-7
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7367136
Gene symbol: Tsku
Gene name: tsukushi, small leucine rich proteoglycan
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 12.0; Tskutm1Koth/Tsku+ (more )
Structure Cell Type Level Pattern Image Note
TS20: epidermis Present 1A Expressed in the undifferentiated epithelium.
TS20: dermis mesenchymal cell Present 1A

Specimen 1B: embryonic day 14.5; Tskutm1Koth/Tsku+ (more )
Structure Cell Type Level Pattern Image Note
TS22: hair epidermal placode Strong 1B Expressed in hair placode cells.
TS22: dermis mesenchymal cell Present 1B

Specimen 1C: embryonic day 16.0; Tskutm1Koth/Tsku+ (more )
Structure Cell Type Level Pattern Image Note
TS24: hair germ Strong 1C Strongly expressed in germ cells.
TS24: dermis mesenchymal cell Present 1C
TS24: hair follicle dermal papilla Weak 1C

Specimen 1D: embryonic day 18.5; Tskutm1Koth/Tsku+ (more )
Structure Cell Type Level Pattern Image Note
TS26: hair peg Strong 1D
TS26: dermis mesenchymal cell Present 1D
TS26: hair follicle dermal papilla Weak 1D

Specimen 1E: postnatal day 0; Tskutm1Koth/Tsku+ (more )
Structure Cell Type Level Pattern Image Note
TS27: hair bulb Strong 1E
TS27: sebaceous gland sebum secreting cell Strong 1E Expressed in sebocytes.
TS27: hair inner root sheath Present 1E
TS27: dermis Absent 1E
TS27: hair follicle dermal papilla Weak 1E

Specimen 1F: postnatal day 2; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS27: hair bulb Strong 1F
TS27: sebaceous gland Strong 1F
TS27: hair outer root sheath Present 1F
TS27: hair follicle bulge Present Regionally restricted 1F Expressed in the bulge cells.
TS27: dermis Absent 1F
TS27: hair follicle dermal papilla Weak 1F

Specimen 1G: postnatal day 4; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair bulb Strong 1G
TS28: sebaceous gland Strong 1G
TS28: dermis Absent 1G
TS28: hair follicle dermal papilla Weak 1G

Specimen 1H: postnatal day 7; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair bulb Strong 1H
TS28: sebaceous gland Strong 1H
TS28: dermis Absent 1H
TS28: hair follicle dermal papilla Weak 1H

Specimen 1I: postnatal day 10; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair bulb Strong 1I
TS28: sebaceous gland Strong 1I
TS28: dermis Absent 1I
TS28: hair follicle dermal papilla Weak 1I

Specimen 1J: postnatal day 16; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1J Expressed in the regressive cells.

Specimen 1K: postnatal day 20; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair bulb Present 1K
TS28: hair follicle bulge Present 1K
TS28: sebaceous gland Present 1K

Specimen 1L: postnatal day 30; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair follicle bulge Present 1L
TS28: sebaceous gland Present 1L

Specimen S2A: postnatal day 20; Tskutm1Koth/Tsku+ (more )
Note: Double labeled: blue - Tsku; brown - Krt15 (assay MGI:7367158).
Structure Level Pattern Image Note
TS28: hair follicle bulge Present S2A Co-localized with Krt15 expression.
TS28: sebaceous gland Present S2A Co-localized with Krt15 expression.

Specimen S2C: postnatal day 20; Tskutm1Koth/Tsku+ (more )
Structure Level Pattern Image Note
TS28: hair bulb Present S2C
TS28: hair follicle bulge Present S2C
TS28: sebaceous gland Present S2C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory