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Gene Expression Data
Assay Details
Assay
Reference: J:316481 Yu D, et al., Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFbeta signaling. Osteoarthritis Cartilage. 2020 Jan;28(1):112-121
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7356580
Gene symbol: Acan
Gene name: aggrecan
Results
Specimen 2c Aggrecan WT: postnatal month 12 (more )
Structure Level Pattern Image Note
TS28: joint articular surface Present 2c Aggrecan WT

Specimen 2c Aggrecan MINK1-/-: postnatal month 12; Mink1tm1.2Lgrl/Mink1tm1.2Lgrl (more )
Structure Level Pattern Image Note
TS28: joint articular surface Weak 2c Aggrecan MINK1-/- Aggrecan degradation neoepitope-positive cells were significantly decreased compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory