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Gene Expression Data
Assay Details
Assay
Reference: J:316481 Yu D, et al., Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFbeta signaling. Osteoarthritis Cartilage. 2020 Jan;28(1):112-121
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7356579
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Results
Specimen 2c COL2A1 WT: postnatal month 12 (more )
Structure Level Pattern Image Note
TS28: joint articular surface Weak Regionally restricted 2c COL2A1 WT Type II collagen degraded at the surface layer.
Specimen 2c COL2A1 MINK1-/-: postnatal month 12; Mink1tm1.2Lgrl/Mink1tm1.2Lgrl (more )
Structure Level Pattern Image Note
TS28: joint articular surface Present Regionally restricted 2c COL2A1 MINK1`-/- Loss of type II collagen protected from surface to deep layer of articular surface.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory