About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:236404 Minocha S, et al., Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification. Dev Biol. 2016 Oct 1;418(1):75-88
Assay type: RNA in situ
MGI Accession ID: MGI:7356411
Gene symbol: Cripto
Gene name: cripto, EGF-CFC family member
Probe: Cripto probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 9Ae: embryonic day 6.5; Hcfc1tm1Lwh/Y (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Regionally restricted 9Ae Expressed in the posterior side.
Specimen 9Ae': embryonic day 6.5; Hcfc1tm1Lwh/Y, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 9Ae' Failed to become restricted to the posterior side.
Specimen 9Ba: embryonic day 7.5; Hcfc1tm1Lwh/Y (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 9Ba
Specimen 9Ba': embryonic day 7.5; Hcfc1tm1Lwh/Y, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present 9Ba' Reduced expression and their graded distribution which marks the anterior-posterior axis was impaired.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory