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Gene Expression Data
Assay Details
Assay
Reference: J:200761 Kasberg AD, et al., SP8 regulates signaling centers during craniofacial development. Dev Biol. 2013 Sep 15;381(2):312-23
Assay type: Western blot
MGI Accession ID: MGI:7355988
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Antibody: Anti-Gli3 (AF3690)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Image: 5H GLI3 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 183 kDa (a) 83 kDa (b) Genetic BackgroundMutant Allele(s)Sex Note
WT E9.5 TS15: face
TS15: neural crest
TS15: neural plate 		Present Present Not Specified Not Specified middle to anterior facial structures including the anterior neural ridge
SP8-/- E9.5 TS15: face
TS15: neural crest
TS15: neural plate 		Present (c) Present (c) involves: 129S1/Sv * 129X1/SvJ Sp8tm1Smb/Sp8tm1SmbNot Specified middle to anterior facial structures including the anterior neural ridge
Notes:
(a) full length (transcriptional activator)
(b) repressor proteins
(c) Reduced expression, although the change was not statistically significant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory