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Gene Expression Data
Assay Details
Assay
Reference: J:74162 Abdelwahid E, et al., Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart. Cell Tissue Res. 2001 Jul;305(1):67-78
Assay type: RNA in situ
MGI Accession ID: MGI:7346368
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 cDNA17
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: interatrial septum Present Regionally restricted 2E , 2F Expression is in the myocardium.
TS20: heart Present Widespread 2E , 2F
TS20: endocardial cushion Present Regionally restricted 2F , 2E Expression is in myocardial and mesenchymal cells adjacent to the interatrial septum.
TS20: atrioventricular valve primordium Weak Regionally restricted 2E , 2F Expression is in the myocardium of the maturing atrioventricular valves.
TS20: atrioventricular canal Weak Regionally restricted 2F , 2E Expression is in the myocardium of the atrioventricular junction.

Specimen 3E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: endocardial cushion Present Regionally restricted 3F , 3E Expression is in the undifferentiated mesenchyme.

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: endocardial cushion Strong Graded 4D , 4C Expression is in the condensed mesenchymal cells in the periphery of the endocardial cushion and decreased gradually from the more differentiated to the immature mesenchyme.

Specimen 6A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract cardiac muscle Present 6B , 6A
TS19: outflow tract endocardial cushion Present 6B , 6A

Specimen 6C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: outflow tract cardiac muscle Present 6C , 6D
TS21: outflow tract endocardial cushion Present 6C , 6D

Specimen not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: endocardial cushion Absent

Specimen not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: atrioventricular canal cardiac muscle Absent
TS17: endocardial cushion Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory