Akt1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:85181 Yang ZZ, et al., Protein kinase B alpha/Akt1 regulates placental development and fetal growth. J Biol Chem. 2003 Aug 22;278(34):32124-31
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7345569
Gene symbol:	Akt1
Gene name:	thymoma viral proto-oncogene 1

Antibody:

anti-PKBalpha

Results

5B +/+ ©

5C +/+ ©

Specimen 5B/C +/+: embryonic day 14.5 (more

)

Structure	Cell Type	Level	Image	Note
TS22: labyrinthine zone		Present	5B +/+ , 5C +/+
TS22: spongiotrophoblast		Present	5B +/+ , 5C +/+
TS22: trophoblast giant cell		Present	5C +/+ , 5B +/+
TS22: extraembryonic blood vessel	endothelial cell of placenta	Present	5B +/+ , 5C +/+
TS28: decidua		Weak	5B +/+ , 5C +/+	Expression was relatively low.

5B -/- ©

5C -/- ©

Specimen 5B/C -/-: embryonic day 14.5; Akt1^tm1Hem/Akt1^tm1Hem (more

)

Structure	Cell Type	Level	Image
TS22: extraembryonic blood vessel	endothelial cell of placenta	Absent	5B -/- , 5C -/-
TS22: labyrinthine zone		Absent	5C -/- , 5B -/-
TS22: spongiotrophoblast		Absent	5B -/- , 5C -/-
TS22: trophoblast giant cell		Absent	5B -/- , 5C -/-
TS28: decidua		Absent	5C -/- , 5B -/-

5D left ©

Specimen 5D left: embryonic day 14.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS22: extraembryonic blood vessel	endothelial cell of placenta	Present		5D left

5D right ©

Specimen 5D right: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: trophoblast giant cell	Present		5D right

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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