Tg(Pomc-lacZ)#Low
Transgene Detail
|
|
| Symbol: |
Tg(Pomc-lacZ)#Low |
| Name: |
transgene insertion, Malcolm J Low |
| MGI ID: |
MGI:7343796 |
| Synonyms: |
-4000rPOMCLacZ |
| Transgene: |
Tg(Pomc-lacZ)#Low Location: unknown
|
| Alliance: |
Tg(Pomc-lacZ)#Low page
|
|
|
|
| Transgene Type: |
|
Transgenic (Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The transgene insert contains 4 kb sequence upstream of the rat Pomc gene transcription start site plus the first 64 bp of the 5' UTR placed upstream of a beta-galactosidase gene cassette. Around half of the 15 mouse lines showed correct pituitary expression and a similar number showed ectopic expression in the brain.
(J:15859)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:15859 Rubinstein M, et al., Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice. Neuroendocrinology. 1993 Oct;58(4):373-80 |
| All: |
1 reference(s) |
|
Analysis Tools
