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Gene Expression Data
Assay Details
Assay
Reference: J:242917 Meng Y, et al., Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017 Jul;246(7):517-530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343564
Gene symbol: Prkcz
Gene name: protein kinase C, zeta
Antibody: Anti-PKC zeta (sc-216; C-20)
Detection system: Alexa Fluor
Results
Specimen 4B WT: embryonic day 6.5 (more )
Note: Double labeled: red - Prkcz; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: embryo Present Regionally restricted 4B WT Merge , 4B WT aPKC The apical lining of the cavity has stronger expression.
Specimen 4B -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Prkcz; green - Dab2 (assay MGI:7343555).
Structure Level Pattern Image Note
TS9: embryo Present 4B - aPKC , 4B - Merge In this mutant expression was evenly distributed in all epiblast cells at the cell-cell junctions, and no asymmetric or concentrated distribution was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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