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Gene Expression Data
Assay Details
Assay
Reference: J:242917 Meng Y, et al., Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017 Jul;246(7):517-530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343549
Gene symbol: Pten
Gene name: phosphatase and tensin homolog
Antibody: anti-Pten (#9188)
Detection system: Alexa Fluor
Results
Specimen 1A WT: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: embryo Present 1A WT Merge , 1A WT Pten
Specimen 1A Pten (-): embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Pten; green - Dab2 (assay MGI:7343555).
Structure Level Pattern Image Note
TS8: embryo Absent 1A - Merge , 1A - Pten
Specimen 3A WT Long.: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3A Long. sec. Merge top , 3A Long. sec. Merge bottom , 3A Long. sec. Pten top , 3A Long. sec. Pten bottom Expression is at the center of the epiblast.
Specimen 3A WT Cross: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3A Cross sec. Merge bottom , 3A Cross sec. Pten top , 3A Cross sec. Pten bottom , 3A Cross sec. Merge top Expression is at the center of the epiblast.
Specimen 3D: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3D Pten , 3D Merge Expression is at the center of the epiblast.
Specimen 3E: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Actin. The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3E Pten , 3E Merge Expression is at the center of the epiblast.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory