About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:242917 Meng Y, et al., Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017 Jul;246(7):517-530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343549
Gene symbol: Pten
Gene name: phosphatase and tensin homolog
Antibody: anti-Pten (#9188)
Detection system: Alexa Fluor
Results
Specimen 1A WT: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: embryo Present 1A WT Merge , 1A WT Pten
Specimen 1A Pten (-): embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Pten; green - Dab2 (assay MGI:7343555).
Structure Level Pattern Image Note
TS8: embryo Absent 1A - Merge , 1A - Pten
Specimen 3A WT Long.: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3A Long. sec. Merge top , 3A Long. sec. Merge bottom , 3A Long. sec. Pten top , 3A Long. sec. Pten bottom Expression is at the center of the epiblast.
Specimen 3A WT Cross: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Dab2 (assay MGI:7343555). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3A Cross sec. Merge bottom , 3A Cross sec. Pten top , 3A Cross sec. Pten bottom , 3A Cross sec. Merge top Expression is at the center of the epiblast.
Specimen 3D: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3D Pten , 3D Merge Expression is at the center of the epiblast.
Specimen 3E: embryonic day 5.5 (more )
Note: Double labeled: red - Pten; green - Actin. The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 3E Pten , 3E Merge Expression is at the center of the epiblast.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory