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Dlx2em1(cre)Zzz
Endonuclease-mediated Allele Detail
Summary
Symbol: Dlx2em1(cre)Zzz
Name: distal-less homeobox 2; endonuclease-mediated mutation 1, Zhuangzhi Zhang
MGI ID: MGI:7341520
Synonyms: Dlx2-Cre
Gene: Dlx2  Location: Chr2:71373752-71377095 bp, - strand  Genetic Position: Chr2, 42.65 cM
Alliance: Dlx2em1(cre)Zzz page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Dlx2em1(cre)Zzz expression driven by 1 gene
 
Mutation detailsUsing CRISPR/Cas9 genome editing, IRES elements and Cre sequences were knocked into the coding region of exon 3 of Dlx2. (J:328873)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dlx2 (mouse)
Summary of all recombinase alleles driven by Dlx2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dlx2 Mutation:  25 strains or lines available
References
Original:  J:328873 Shang Z, et al., The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory