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Gene Expression Data
Assay Details
Assay
Reference: J:216076 Hou C, et al., Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice. Dev Biol. 2014 Nov 1;395(1):167-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7341506
Gene symbol: Nes
Gene name: nestin
Antibody: anti-Nestin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5Ba/c/g: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebellum neural progenitor cell Present 5Bc , 5Ba , 5Bg Positive cells were positioned in an orderly manner. Only few clusters in wild-type cerebellum were seen.
Specimen 5Bd/f/h: embryonic day 13.5; Llgl1tm1Vv/Llgl1tm1Vv, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: cerebellum neural progenitor cell Present 5Bh , 5Bf , 5Bd Expression was much stronger compared to wild-type embryos (quantified in Fig 5D). Rosettes-like clusters, projecting from a centre to all directions, were seen.
Specimen not shown: embryonic day 12.5; Llgl1tm1Vv/Llgl1tm1Vv, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: cerebellum primordium neural progenitor cell Present Expression was much stronger compared to wild-type embryos.
Specimen not shown: embryonic day 14.5; Llgl1tm1Vv/Llgl1tm1Vv, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS22: cerebellum neural progenitor cell Present Expression was much stronger compared to wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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