Gene Expression Data
Assay Details
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Assay
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Reference:
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J:237675
Wyler SC, et al., Pet-1 Controls Tetrahydrobiopterin Pathway and Slc22a3 Transporter Genes in Serotonin Neurons. ACS Chem Neurosci. 2015 Jul 15;6(7):1198-205
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7341500
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Gene symbol:
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Htr1a
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Gene name:
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5-hydroxytryptamine (serotonin) receptor 1A
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Probe:
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Htr1a cDNA3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5I:
postnatal adult
(more  )
Note: Fig. 5 showed sections through the entire dorsal raphe in an anterior to posterior series. 5I - Anterior-most section of wild type dorsal raphe.
Specimen
5I:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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Fig. 5 showed sections through the entire dorsal raphe in an anterior to posterior series. 5I - Anterior-most section of wild type dorsal raphe.
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Specimen
5J:
postnatal adult
(more )
Specimen
5J:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
5K:
postnatal adult
(more )
Specimen
5K:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
5L:
postnatal adult
(more )
Note: 5L - Posterior-most section of wild type dorsal raphe.
Specimen
5L:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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5L - Posterior-most section of wild type dorsal raphe.
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Specimen
5M:
postnatal adult; Fevtm1Esd/ Fevtm1Esd
(more )
Note: 5M - Anterior-most section of Pet-1-/- dorsal raphe.
Specimen
5M:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fevtm1Esd/Fevtm1Esd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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5M - Anterior-most section of Pet-1-/- dorsal raphe.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal raphe nucleus |
Weak |
Uniform |
5M
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Few, if any, cells in the mutant dorsal raphe had expression at levels similar to wild type. The low, uniform level might be background signal, low residual expression in serotonergic neurons, or normal expression in non-serotonergic cells.
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Specimen
5N:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fevtm1Esd/Fevtm1Esd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal raphe nucleus |
Weak |
Uniform |
5N
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Few, if any, cells in the mutant dorsal raphe had expression at levels similar to wild type. The low, uniform level might be background signal, low residual expression in serotonergic neurons, or normal expression in non-serotonergic cells.
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Specimen
5O:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fevtm1Esd/Fevtm1Esd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal raphe nucleus |
Weak |
Uniform |
5O
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Few, if any, cells in the mutant dorsal raphe had expression at levels similar to wild type. The low, uniform level might be background signal, low residual expression in serotonergic neurons, or normal expression in non-serotonergic cells.
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Specimen
5P:
postnatal adult; Fevtm1Esd/ Fevtm1Esd
(more )
Note: 5P - Posterior-most section of Pet-1-/- dorsal raphe.
Specimen
5P:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fevtm1Esd/Fevtm1Esd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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5P - Posterior-most section of Pet-1-/- dorsal raphe.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal raphe nucleus |
Weak |
Uniform |
5P
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Few, if any, cells in the mutant dorsal raphe had expression at levels similar to wild type. The low, uniform level might be background signal, low residual expression in serotonergic neurons, or normal expression in non-serotonergic cells.
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Analysis Tools