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Gene Expression Data
Assay Details
Assay
Reference: J:306318 Ono K, et al., Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2. Commun Biol. 2021 Mar 11;4(1):326
Assay type: RNA in situ
MGI Accession ID: MGI:7339224
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh cDNA19
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5a WT: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: tibia cartilage condensation growth plate cartilage chondrocyte Present Regionally restricted 5a Ihh WT Expressed in the pre-hypertrophic chondrocyte zone.
Specimen 5a -/-: embryonic day 14.5; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Structure Cell Type Level Pattern Image Note
TS22: tibia cartilage condensation growth plate cartilage chondrocyte Weak Regionally restricted 5a Ihh Dmrt2-/- Reduced expression in the pre-hypertrophic chondrocyte zone.
Specimen 5b WT: embryonic day 15.0 (more )
Structure Cell Type Level Pattern Image Note
TS23: epiphyseal plate growth plate cartilage chondrocyte Present Regionally restricted 5b Ihh WT Expressed in the pre-hypertrophic chondrocyte zone.
Specimen 5b -/-: embryonic day 15.0; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Structure Cell Type Level Pattern Image Note
TS23: epiphyseal plate growth plate cartilage chondrocyte Present Regionally restricted 5b Ihh Dmrt2-/- Positive pre-hypertrophic zones were significantly shorter than in wild-type.
Specimen S6b WT: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: rib cartilage chondrocyte Present Regionally restricted S6b Ihh WT Expressed in pre-hypertrophic chondrocytes.
Specimen S6b -/-: postnatal newborn; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Structure Cell Type Level Pattern Image Note
TS27: rib cartilage chondrocyte Present Regionally restricted S6b Ihh Dmrt2-/- Expressed in pre-hypertrophic chondrocytes, which was shortened relative to that in wild-type mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory