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Gene Expression Data
Assay Details
Assay
Reference: J:306318 Ono K, et al., Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2. Commun Biol. 2021 Mar 11;4(1):326
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7339221
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Antibody: anti-collagen type X (LSL LB-0092)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 2C: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: epiphyseal plate hypertrophic zone hypertrophic chondrocyte Present 2c Col10
TS23: epiphyseal plate Present Regionally restricted 2c Col10 Expressed in pre-hypertrophic chondrocytes.
Specimen 4g WT: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: rib cartilage hypertrophic chondrocyte Present Regionally restricted 4g WT Col10 Expressed in the hypertrophic chondrocyte zone.
Specimen 4g -/-: postnatal day 0; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Structure Cell Type Level Pattern Image Note
TS27: rib cartilage hypertrophic chondrocyte Present Regionally restricted 4g -/- Col10 Expressed in the hypertrophic chondrocyte zone, which was shortened relative to that in wild-type mice.
Specimen 4h WT: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: sternum chondrocyte Present 4h WT Col10
Specimen 4h -/-: postnatal day 0; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Structure Cell Type Level Pattern Image Note
TS27: sternum chondrocyte Present 4h -/- Col10 Positive chondrocytes were disorganized relative to the pattern in wild-type mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory