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Gene Expression Data
Assay Details
Assay
Reference: J:306318 Ono K, et al., Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2. Commun Biol. 2021 Mar 11;4(1):326
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7339220
Gene symbol: Dmrt2
Gene name: doublesex and mab-3 related transcription factor 2
Antibody: anti-Dmrt2 (ARP32224-P050)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 2C: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: long bone epiphyseal plate growth plate cartilage chondrocyte Strong 2c Dmrt2 Highly expressed in pre-hypertrophic chondrocytes.
TS23: long bone epiphyseal plate hypertrophic zone hypertrophic chondrocyte Weak 2c Dmrt2
TS23: long bone epiphyseal plate proliferative zone growth plate cartilage chondrocyte Weak 2c Dmrt2

Specimen S4b: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: long bone epiphysis Present Regionally restricted S4b Expressed in pre-hypertrophic chondrocytes around the secondary ossification center.

Specimen S4d: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: long bone epiphyseal plate Weak S4d Expression level was low in the growth plate.

Specimen S5b: embryonic day 15.5 (more )
Note: Double labeled: red - Dmrt2; green - Sox9 (assay MGI:7339226).
Structure Cell Type Level Pattern Image Note
TS23: long bone epiphyseal plate growth plate cartilage chondrocyte Present S5b Merge , S5b Dmrt2 Coexpressed with Sox9.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory