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Gene Expression Data
Assay Details
Assay
Reference: J:264603 Da Silva F, et al., Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51
Assay type: RNA in situ
MGI Accession ID: MGI:7336783
Gene symbol: Rspo3
Gene name: R-spondin 3
Probe: Rspo3 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1Ai/ii: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Strong Regionally restricted 1Ai , 1Aii Expressed in the area near the developing coronary stems.
Specimen 1Aiii: embryonic day 14.5 (more )
Note: Double labeled: purple - Rspo3; red - myosin/MF20.
Structure Cell Type Level Pattern Image Note
TS22: cardiac muscle tissue fetal cardiomyocyte Strong Regionally restricted 1Aiii Expressed in the area near the developing coronary stems. Coexpressed with myocyte-specific myosin heavy chain 1E (MF20).
Specimen S1A Pax3-cKO: embryonic day 14.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Pax3tm1(cre)Joe/Pax3+, Rspo3tm2Okam/Rspo3tm2Okam (more )
Note: Conditional mutant. Double labeled: purple - Rspo3; brown - Cre reporter.
Structure Level Pattern Image Note
TS22: heart Strong Regionally restricted S1A left Expressed in the area near the developing coronary stems. Not co-expressed with cardiac neural crest cell linage (Pax3-cre+).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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