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Gene Expression Data
Assay Details
Assay
Reference: J:172620 Ogawa T, et al., Distribution of the longevity gene product, SIRT1, in developing mouse organs. Congenit Anom (Kyoto). 2011 Jun;51(2):70-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7336746
Gene symbol: Sirt1
Gene name: sirtuin 1
Antibody: Anti-Sirt1 (07-131)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Vibrotome sections were stained in a free-floating manner.
Results
Specimen 1-1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Strong Regionally restricted 1_1 Expression was detected in the neuroepithelium.

Specimen 1-2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: olfactory epithelium Strong 1_2

Specimen 1-3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart Present 1_3

Specimen 1-4: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Strong 1_4
TS19: future spinal cord Strong 1_4

Specimen 1-5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: eye Strong Regionally restricted 1_5 Expression was detected in the optic cup.
TS19: lens primordium Strong 1_5

Specimen 1-6: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst Strong 1_6

Specimen 2-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vibrissa bulb Strong Regionally restricted 2_1 Expression was detected in hair root of whiskers.

Specimen 2-2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens Strong 2_2
TS22: retina Strong 2_2

Specimen 2-3: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal cavity epithelium Strong 2_3

Specimen 2-4: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Strong 2_4
TS22: telencephalon Strong Regionally restricted 2_4 Expression was detected in neuroepithelium.

Specimen 2-5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Strong 2_5

Specimen 2-6: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum layer Strong Regionally restricted 2_6 Expression was detected in external germinal layer of cerebellum.

Specimen 2-7: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: brainstem nucleus Strong Regionally restricted 2_7 Expression was detected in prepositus glossal nucleus.
TS22: hindbrain neuron Strong Regionally restricted 2_7 Expression was detected in large neurons of the pontomedullary area.

Specimen 3-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung Strong 3_1

Specimen 3-2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Strong 3_2

Specimen 3-3: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver Strong 3_3

Specimen 3-4: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong 3_4
TS22: spinal cord Present 3_4

Specimen 3-5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal tubule Strong 3_5
TS22: renal vesicle Strong 3_5

Specimen 3-6: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: testis Very strong Regionally restricted 3_6 Expression was very strong in the spermatogonium.

Specimen 3-7: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gut mucosa Present 3_7

Specimen 3-8: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach Present 3_8

Specimen 4-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver Strong 4_1

Specimen 4-2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: liver Weak 4_2

Specimen 4-3: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: liver Trace 4_3

Specimen 4-4: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: liver Trace 4_4

Specimen 4-5: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: liver Trace 4_5

Specimen 4-6: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: liver Trace 4_6

Specimen 5-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal vesicle Strong 5_1

Specimen 5-2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: metanephros Present Regionally restricted 5_2 After E14.5, expression gradually decreased in the Bowman capsule, and the collecting tubule, but not the glomerulus, depending on age.

Specimen 5-3: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted 5_3 After E14.5, expression gradually decreased in the Bowman capsule, and the collecting tubule, but not the glomerulus, depending on age.

Specimen 5-4: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: metanephros Present Regionally restricted 5_4 After E14.5, expression gradually decreased in the Bowman capsule, and the collecting tubule, but not the glomerulus, depending on age.

Specimen 5-5: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: metanephros Present Regionally restricted 5_5 After E14.5, expression gradually decreased in the Bowman capsule, and the collecting tubule, but not the glomerulus, depending on age.

Specimen 5-6: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: collecting duct Weak 5_6
TS28: renal tubule Weak Regionally restricted 5_6 Weak expression remained in the uriniferous tubule.

Specimen 6-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Strong 6_1

Specimen 6-2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cardiac muscle tissue Strong 6_2

Specimen 6-3: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cardiac muscle tissue Strong 6_3

Specimen 6-4: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cardiac muscle tissue Strong 6_4

Specimen 6-5: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Strong 6_5

Specimen 6-6: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Strong 6_6

Specimen 7-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung Strong 7_1

Specimen 7-2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung Strong 7_2

Specimen 7-3: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lung Strong 7_3

Specimen 7-4: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: lung Strong 7_4

Specimen 7-5: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: lung Strong Regionally restricted 7_5 Expression remained in the structures surrounding the alveolus.

Specimen 7-6: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: lung Present 7_6 There tended to be a decrease in reactivity between P11 and P16.

Specimen 8-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: testis Very strong Regionally restricted 8_1 Expression was very strong in the spermatogonium.

Specimen 8-2: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spermatogonium Strong 8_2
TS27: seminiferous tubule Strong Widespread 8_2 Expression was distributed in most cells in the seminiferous tubules at all stages of spermatogenesis.

Specimen 8-3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: spermatogonium Strong 8_3
TS27: seminiferous tubule Strong Widespread 8_3 Expression was distributed in most cells in the seminiferous tubules at all stages of spermatogenesis.

Specimen 8-4: postnatal day 6 (more )
Structure Level Pattern Image Note
TS27: spermatogonium Strong 8_4
TS27: seminiferous tubule Strong Widespread 8_4 Expression was distributed in most cells in the seminiferous tubules at all stages of spermatogenesis.

Specimen 8-5: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: spermatogonium Strong 8_5
TS28: seminiferous tubule Strong Widespread 8_5 Expression was distributed in most cells in the seminiferous tubules at all stages of spermatogenesis.

Specimen 8-6: postnatal month 11 (more )
Structure Level Pattern Image Note
TS28: spermatogonium Strong 8_6
TS28: seminiferous tubule Strong Widespread 8_6 Expression was distributed in most cells in the seminiferous tubules at all stages of spermatogenesis.

Specimen 9-1: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex neural progenitor cell Present Regionally restricted 9_1 Expression was detected in the neuroepithelial layer (the stem cells and progenitor cells).
TS26: cortical plate neuron Present 9_1

Specimen 9-2: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex neural progenitor cell Present Regionally restricted 9_2 Expression was detected in the neuroepithelial layer (the stem cells and progenitor cells).
TS27: cortical plate neuron Present 9_2

Specimen 9-3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present 9_3

Specimen 9-4-1: postnatal day 11 (more )
Note: Outer layers of the cerebral cortex.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 9_4-1

Specimen 9-4-2: postnatal day 11 (more )
Note: Deeper layers of the cerebral cortex.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 9_4-2

Specimen 9-5: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 9_5 Immunoreactivity remained, but with a tendency of decrease until P18.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory