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Tg(Eno2-IL6)15Gci
Transgene Detail
Summary
Symbol: Tg(Eno2-IL6)15Gci
Name: transgene insertion 15, Gennaro Ciliberto
MGI ID: MGI:7336000
Synonyms: NSE/hIL-6 Tg
Transgene: Tg(Eno2-IL6)15Gci  Location: unknown  
Alliance: Tg(Eno2-IL6)15Gci page
Transgene
origin
Strain of Origin:  (C57BL/6 x BALB/c)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Eno2-IL6)15Gci expresses 1 gene
    Expression of a human IL6 cDNA is driven by a 1.8 kb rat Eno2 (NSE) promoter fragment. (J:128179)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:128179 Fattori E, et al., IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage. Eur J Neurosci. 1995 Dec 1;7(12):2441-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory