Gene Expression Data
Assay Details
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Assay
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Reference:
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J:161878
Hudon V, et al., Renal tumour suppressor function of the Birt-Hogg-Dube syndrome gene product folliculin. J Med Genet. 2010 Mar;47(3):182-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7334798
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Gene symbol:
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Flcn
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Gene name:
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folliculin
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Antibody:
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anti-FLCN
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Assay notes:
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Two antibodies were mentioned in the paper. It was not specified which one was used.
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Results
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Specimen
2B:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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FlcnGt(RRX115)Byg/Flcn+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: renal proximal tubule |
Present |
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2B
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Co-localized with the proximal tubule marker Lotus tetragonolobus agglutinin (LTA).
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Specimen
2D:
postnatal adult; FlcnGt(RRX115)Byg/Flcn +
(more  )
Note: tissue around renal cyst
Specimen
2D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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FlcnGt(RRX115)Byg/Flcn+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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tissue around renal cyst
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: renal proximal tubule |
Present |
Regionally restricted |
2D
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Expression was lost in the epithelial lining of the cysts and in the surrounding cyst-associated tissues.
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Analysis Tools
