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Gene Expression Data
Assay Details
Assay
Reference: J:307271 Airik M, et al., Loss of Anks6 leads to YAP deficiency and liver abnormalities. Hum Mol Genet. 2020 Nov 4;29(18):3064-3080
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7333217
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: Anti-Sox9 (AB5535)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5A: embryonic day 15.5 (more )
Note: Double labeled: red - Sox9; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: intrahepatic bile duct Present Regionally restricted 5A Expression in ductal plate structures, including single layered ductal plate

Specimen 5B: embryonic day 15.5 (more )
Note: Double labeled: red - Sox9; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: intrahepatic bile duct epithelium Present Regionally restricted 5B Expression in double-layered epithelial formations.

Specimen 5C: embryonic day 15.5; Anks6tm1d(KOMP)Wtsi/Anks6tm1d(KOMP)Wtsi (more )
Note: Double labeled: red - Sox9; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: intrahepatic bile duct Present Scattered 5C Expression in scattered cells surrounding portal vein.

Specimen 5D: embryonic day 15.5; Anks6tm1d(KOMP)Wtsi/Anks6tm1d(KOMP)Wtsi (more )
Note: Double labeled: red - Sox9; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: intrahepatic bile duct epithelium Present Regionally restricted 5D Expression in tubule-like aggregates.

Specimen 5E: embryonic day 18.5 (more )
Note: Double labeled: red - Sox9; green - Ctnnb1 (assay MGI:7333219).
Structure Level Pattern Image Note
TS26: intrahepatic bile duct epithelium Present Widespread 5E Uniform expression in entire bilary epithelium.

Specimen 5F: embryonic day 18.5; Anks6tm1d(KOMP)Wtsi/Anks6tm1d(KOMP)Wtsi (more )
Note: Double labeled: red - Sox9; green - Ctnnb1 (assay MGI:7333219).
Structure Level Pattern Image Note
TS26: intrahepatic bile duct epithelium Present Regionally restricted 5F Expression in portal side (first ductal layer) of bile ducts, but not on parenchymal side of biliary epithelium.

Specimen 5G: embryonic day 18.5; Anks6tm1d(KOMP)Wtsi/Anks6tm1d(KOMP)Wtsi (more )
Note: Double labeled: red - Sox9; green - Ctnnb1 (assay MGI:7333219).
Structure Level Pattern Image Note
TS26: intrahepatic bile duct epithelium Present Regionally restricted 5G Expression in portal side (first ductal layer) of bile ducts, but not on parenchymal side of biliary epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory