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Tg(DMD*)37del52Lumc
Transgene Detail
Summary
Symbol: Tg(DMD*)37del52Lumc
Name: transgene insertion 37del52, Leiden University Medical Centre
MGI ID: MGI:7333165
Synonyms: del52hDMD/mdx#37, hDMDdel52-low
Transgene: Tg(DMD*)37del52Lumc  Location: unknown  Genetic Position: Chr5, Syntenic
Alliance: Tg(DMD*)37del52Lumc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:257449
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  STOCK Tg(DMD)72Thoen Dmdmdx/Lumc
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(DMD*)37del52Lumc expresses 1 gene
 
Mutation detailsThe targeting construct deleted exon 52 from both copies of the transgene. Loss of exon 52 results very low DMD protein expression from the transgene insertion. (J:257449)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:257449 Veltrop M, et al., A dystrophic Duchenne mouse model for testing human antisense oligonucleotides. PLoS One. 2018;13(2):e0193289
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory