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Gene Expression Data
Assay Details
Assay
Reference: J:153743 Purcell P, et al., Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302
Assay type: RNA in situ
MGI Accession ID: MGI:7331469
Gene symbol: Zfp445
Gene name: zinc finger protein 445
Probe: Zfp445 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1G: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: mandible condylar process chondrocyte Strong Regionally restricted 1G Expression is in proliferating chondrocytes.
TS24: mandibular fossa Present 1G
TS24: temporo-mandibular joint disc Present 1G
TS24: mandible condylar process hypertrophic chondrocyte Weak Regionally restricted 1G Expression is down-regulated in hypertrophic chondrocytes.

Specimen 3J TMJ: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible condylar process Strong Regionally restricted 3J TMJ Expression is at the tip of the condyle.

Specimen 3J Shoulder: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Uniform 3J Shoulder
TS22: scapula cartilage condensation Present Uniform 3J Shoulder

Specimen 3J hip: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: femur cartilage condensation Present Uniform 3J hip
TS22: ilium cartilage condensation Present Uniform 3J hip

Specimen 5H: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible condylar process chondrocyte Present Regionally restricted 5H Expression is in proliferating chondrocytes.

Specimen 5K: embryonic day 18.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible condylar process chondrocyte Weak 5K


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory