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Gene Expression Data
Assay Details
Assay
Reference: J:153743 Purcell P, et al., Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302
Assay type: RNA in situ
MGI Accession ID: MGI:7331466
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe69
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1F: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: mandible condylar process chondrocyte Strong Regionally restricted 1F Expression is in proliferating chondrocytes.
TS24: mandible condylar process hypertrophic chondrocyte Weak Regionally restricted 1F Expression is down-regulated in hypertrophic chondrocytes.
Specimen 3I TMJ: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible condylar process Strong Regionally restricted 3I TMJ Expression is at the tip of the condyle.
TS24: mandibular fossa Absent 3I TMJ
Specimen 3I Shoulder: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Uniform 3I Shoulder
TS22: scapula cartilage condensation Present Uniform 3I Shoulder
Specimen 3I hip: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: femur cartilage condensation Present Uniform 3I hip
TS22: ilium cartilage condensation Present Uniform 3I hip
Specimen 5I: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible condylar process chondrocyte Present Regionally restricted 5I Expression is in proliferating chondrocytes.
Specimen 5L: embryonic day 18.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible condylar process chondrocyte Present Regionally restricted 5L Expression in this mutant is similar to wild-type despite a reduction in cells in the chondroprogenitor layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory