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Gene Expression Data
Assay Details
Assay
Reference: J:325976 Piprek RP, et al., Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads. Reproduction. 2022 Feb 24;163(4):199-207
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7330135
Gene symbol: Gcna
Gene name: germ cell nuclear acidic protein
Antibody: TRA98 (ab82527)
Assay notes: Genetic background of control specimens was either Dsp1fl/fl or Nr5a1-Cre.
Results
Specimen 2C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: germ cell of testis Present 2C Many germ cells in control testis.
Specimen 2D: embryonic day 18.5; Dsptm1Efu/Dsptm1Efu, Tg(Nr5a1-cre)7Lowl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: germ cell of testis Trace Single cells 2D Authors report reduction in germ cell number. Few germ cells in knockout testis.
Specimen 2E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: germ cell of ovary Present 2E Many germ cells in control ovary.
Specimen 2F: embryonic day 18.5; Dsptm1Efu/Dsptm1Efu, Tg(Nr5a1-cre)7Lowl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: germ cell of ovary Trace Single cells 2F Authors report reduction in germ cell number.
TS26: surface epithelium of ovary Trace Single cells 2F Few germ cells in surface epithelium of knockout ovary.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
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