About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:255320 Pederick DT, et al., Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy. Neuron. 2018 Jan 3;97(1):59-66.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7329952
Gene symbol: Sox3
Gene name: SRY (sex determining region Y)-box 3
Antibody: anti-Sox3 (AF2569)
Detection system: Secondary antibody
Results
Specimen S3B left: embryonic day 13.5; Sox3em2Pqt/Sox3+ (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted S3B SOX3 left This cortex shows normal X-inactivation.
Specimen S3B right: embryonic day 13.5; Pcdh19tm1Tac/Pcdh19+, Sox3em2Pqt/Sox3+ (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted S3B SOX3 right This cortex shows abnormal cell sorting of positive and negative neural progenitor cells.
Specimen S3C: embryonic day 8.5; Pcdh19em1Pqt/Y (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS13: neural ectoderm Present S3C right
Specimen S3D top: embryonic day 9.5; Pcdh19em1Pqt/Y (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS15: telencephalon Present S3D top
Specimen S3D middle: embryonic day 9.5; Pcdh19em1Pqt/Pcdh19+ (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS15: telencephalon Present S3D middle
Specimen S3D bottom: embryonic day 9.5; Pcdh19tm1Tac/Pcdh19em1Pqt (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS15: telencephalon Present S3D bottom
Specimen S3E top: embryonic day 10.5; Pcdh19em1Pqt/Y (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS17: telencephalon Present S3E top
Specimen S3E middle: embryonic day 10.5; Pcdh19em1Pqt/Pcdh19+ (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS17: telencephalon Present S3E middle
Specimen S3E bottom: embryonic day 10.5; Pcdh19tm1Tac/Pcdh19em1Pqt (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS17: telencephalon Present S3E bottom
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory