Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Tek-EPHX2)#Dcz
Name:	transgene insertion, Darryl Zeldin
MGI ID:	MGI:7328790
Synonyms:	Tie2-sEH Tr
Transgene:	Tg(Tek-EPHX2)#Dcz  Location: unknown
Alliance:	Tg(Tek-EPHX2)#Dcz page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Tek-EPHX2)#Dcz expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human EPHX2 (2053) Ephx2  (MGI:99500)   Mutation details: The human EPHX2 cDNA (NM001979) cDNA sequence was subcloned downstream of the murine Tek promoter and upstream of the Tek full enhancer sequences to drive endothelial expression in mice. The pound # sign is used in the allele symbol where the line is not specified. (J:263594)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:263594 Edin ML, et al., Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J. 2011 Oct;25(10):3436-47
All:	9 reference(s)