Tg(Col2a1-Runx2)1Tok
Transgene Detail
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| Symbol: |
Tg(Col2a1-Runx2)1Tok |
| Name: |
transgene insertion 1, Toshihisa Komori |
| MGI ID: |
MGI:2447357 |
| Synonyms: |
Col2a1-type I Cbfa1 |
| Transgene: |
Tg(Col2a1-Runx2)1Tok Location: unknown
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| Alliance: |
Tg(Col2a1-Runx2)1Tok page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Col2a1-Runx2)1Tok expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Runx2 (MGI:99829) |
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Mutation details: The entire coding region of mouse Runx2 (with translation starting from exon 2) was cloned between the promoter and enhancer elements of Col2a1, which were used to drive transgene expression in chondrocytes. Transgene expression was confirmed by Northern blot analysis of RNA extracted from the head or trunk of day E12.5 transgenic embryos. Both type I and type II isoforms are expressed from this transgene.
(J:68793)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:68793 Ueta C, et al., Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol. 2001 Apr 2;153(1):87-100 |
| All: |
1 reference(s) |
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Analysis Tools
